ADCK5

aarF domain containing kinase 5 | FLJ35454

Predicted to enable protein serine/threonine kinase activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 3 terms

membrane (GO:0016020)mitochondrion (GO:0005739)protein binding (GO:0005515)

Expression (TPM)

TFs regulating ADCK5 0 TFs

Transcription factors with Perturb-seq knockdown data for ADCK5. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ADCK5 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to ADCK5

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ADCK5, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr8:144,078,142–144,079,235	295.4 kb	Distal (>10kb) Multiome	912
chr8:144,082,187–144,083,105	291.5 kb	Distal (>10kb) Multiome	763
chr8:144,094,454–144,095,491	279.1 kb	Distal (>10kb) Multiome	798
chr8:144,103,485–144,105,242	269.7 kb	Distal (>10kb) Multiome	1033
chr8:144,108,038–144,108,663	265.7 kb	Distal (>10kb) Multiome	137
chr8:144,137,565–144,138,500	236.3 kb	Distal (>10kb) Multiome	817
chr8:144,146,820–144,149,073	226.1 kb	Distal (>10kb) Multiome	790
chr8:144,266,293–144,267,098	107.6 kb	Distal (>10kb) Multiome	162
chr8:144,290,981–144,292,410	82.5 kb	Distal (>10kb) Multiome	716
chr8:144,315,833–144,316,450	57.9 kb	Distal (>10kb) Multiome	396
chr8:144,325,768–144,327,719	47.1 kb	Distal (>10kb) Multiome	1016
chr8:144,331,281–144,333,847	42.1 kb	Distal (>10kb) Multiome	406
chr8:144,336,102–144,339,119	37.2 kb	Distal (>10kb) Multiome	922
chr8:144,353,907–144,355,227	19.5 kb	Distal (>10kb) Multiome	280
chr8:144,358,142–144,359,070	15.5 kb	Distal (>10kb) Multiome	719
chr8:144,369,349–144,369,916	4.3 kb	Proximal (<10kb) Multiome	204
chr8:144,372,497–144,372,883	1.3 kb	Proximal (<10kb) Multiome	160
chr8:144,372,993–144,375,084	88 bp	At TSS Multiome	903
chr8:144,408,968–144,410,189	35.4 kb	Distal (>10kb) Multiome HiCAR	920
chr8:144,427,691–144,429,571	54.5 kb	Distal (>10kb) Multiome HiCAR	1000
chr8:144,443,691–144,445,047	70.3 kb	Distal (>10kb) Multiome HiCAR	743
chr8:144,462,568–144,463,422	88.9 kb	Distal (>10kb) Multiome	548
chr8:144,463,885–144,468,178	91.7 kb	Distal (>10kb) Multiome	910
chr8:144,471,960–144,474,391	98.5 kb	Distal (>10kb) Multiome	482
chr8:144,474,517–144,476,543	101.8 kb	Distal (>10kb) Multiome	321
chr8:144,477,277–144,478,749	103.9 kb	Distal (>10kb) Multiome	679
chr8:144,478,851–144,479,509	105.3 kb	Distal (>10kb) Multiome	392
chr8:144,483,979–144,484,843	110.3 kb	Distal (>10kb) Multiome	125
chr8:144,495,748–144,496,431	122.0 kb	Distal (>10kb) Multiome	131
chr8:144,500,182–144,501,505	127.0 kb	Distal (>10kb) Multiome	484
chr8:144,507,995–144,510,268	134.8 kb	Distal (>10kb) Multiome	1067
chr8:144,517,168–144,518,442	143.9 kb	Distal (>10kb) Multiome	637
chr8:144,521,935–144,523,450	148.5 kb	Distal (>10kb) Multiome	663
chr8:144,524,105–144,525,099	150.6 kb	Distal (>10kb) Multiome	264
chr8:144,526,399–144,529,305	153.0 kb	Distal (>10kb) Multiome	934
chr8:144,529,455–144,530,630	156.1 kb	Distal (>10kb) Multiome	284
chr8:144,580,290–144,581,657	206.7 kb	Distal (>10kb) Multiome	271
chr8:144,672,507–144,672,989	298.8 kb	Distal (>10kb) Multiome	150

Genome Browser

Genomic view of the ADCK5 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.