Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be involved in protein depalmitoylation. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ABHD13. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ABHD13 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ABHD13, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr13:108,214,207–108,214,853 | 3.5 kb | Proximal (<10kb) | 113 | |
| chr13:108,215,115–108,215,948 | 2.8 kb | Proximal (<10kb) Multiome | 468 | |
| chr13:108,217,843–108,219,001 | 54 bp | At TSS Multiome | 875 | |
| chr13:108,220,124–108,220,305 | 1.7 kb | Proximal (<10kb) | 53 | |
| chr13:108,494,655–108,497,208 | 277.6 kb | Distal (>10kb) Multiome | 402 |
Genomic view of the ABHD13 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.