New paper: Human pancreatic progenitor organoids define genetic and epigenetic barriers to early PDAC transformation. Developmental Cell. Publication

New paper: Functional chromatin signatures premark future lineage-specific enhancers. Cell Genomics. Publication

Denis Torre awarded the Damon Runyon Cancer Research Foundation Fellowship. Fellowship

Tamara Casteels receives the Emerald Foundation Postdoctoral Fellowship. Fellowship

Pallavi Mohapatra receives the Kaufman Family Postdoctoral Fellowship in Pediatric Cancer. Fellowship

New paper: Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells. Stem Cell Reports. Publication

Renhe Luo receives the GSK Chairman's Prize. Award

New paper: Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness. Nature Communications. Publication

New paper: CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant. Cell Reports. Publication

New paper: Glucose Transporters Are Key Components of the Human Glucostat. Diabetes. Publication

The lab launches the MSK MorPhiC Project, a systematic effort to functionally characterize noncoding elements in the human genome. Project

New paper: CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction. Nature Cell Biology. Publication

New paper: Epigenome rewiring in human pluripotent stem cells. Trends in Cell Biology. Publication

New paper: QSER1 protects DNA methylation valleys from de novo methylation. Science. Publication

New paper: Enhancer Predictions and Genome-Wide Regulatory Circuits. Annual Review of Genomics and Human Genetics. Publication