Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF79. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF79 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF79, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:127,129,382–127,130,064 | 294.8 kb | Distal (>10kb) Multiome | 117 | |
| chr9:127,199,063–127,199,676 | 225.0 kb | Distal (>10kb) Multiome | 315 | |
| chr9:127,223,725–127,226,151 | 199.6 kb | Distal (>10kb) Multiome | 713 | |
| chr9:127,244,905–127,245,629 | 179.1 kb | Distal (>10kb) Multiome | 447 | |
| chr9:127,396,281–127,398,388 | 27.4 kb | Distal (>10kb) Multiome | 843 | |
| chr9:127,418,109–127,418,344 | 6.0 kb | Proximal (<10kb) | 167 | |
| chr9:127,423,809–127,424,734 | 79 bp | At TSS Multiome | 791 | |
| chr9:127,450,607–127,452,473 | 27.0 kb | Distal (>10kb) Multiome | 1009 | |
| chr9:127,567,936–127,569,972 | 144.8 kb | Distal (>10kb) Multiome | 660 | |
| chr9:127,608,129–127,608,913 | 184.1 kb | Distal (>10kb) Multiome | 700 | |
| chr9:127,611,734–127,612,761 | 187.8 kb | Distal (>10kb) Multiome | 566 | |
| chr9:127,699,155–127,699,632 | 275.1 kb | Distal (>10kb) Multiome | 440 | |
| chr9:127,715,013–127,716,345 | 291.4 kb | Distal (>10kb) Multiome | 735 |
Genomic view of the ZNF79 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.