WASHC1

WASH complex subunit 1 | FLJ00038, FAM39E, WASH1

Enables alpha-tubulin binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including Arp2/3 complex-mediated actin nucleation; endosomal transport; and positive regulation of pseudopodium assembly. Located in several cellular components, including endosome; exocyst; and lamellipodium. Part of WASH complex. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 42 terms

Arp2/3 complex-mediated actin nucleation (GO:0034314)Arp2/3 complex-mediated actin nucleation (GO:0034314)Arp2/3 complex-mediated actin nucleation (GO:0034314)Arp2/3 complex-mediated actin nucleation (GO:0034314)WASH complex (GO:0071203)WASH complex (GO:0071203)WASH complex (GO:0071203)alpha-tubulin binding (GO:0043014)alpha-tubulin binding (GO:0043014)autophagosome (GO:0005776)autophagosome (GO:0005776)centriole (GO:0005814)cytosol (GO:0005829)early endosome (GO:0005769)early endosome (GO:0005769)early endosome (GO:0005769)early endosome (GO:0005769)early endosome membrane (GO:0031901)early endosome membrane (GO:0031901)endocytic recycling (GO:0032456)endocytic recycling (GO:0032456)endosomal transport (GO:0016197)endosomal transport (GO:0016197)exocyst (GO:0000145)exocytosis (GO:0006887)exocytosis (GO:0006887)extracellular matrix disassembly (GO:0022617)late endosome (GO:0005770)negative regulation of autophagy (GO:0010507)phosphatidylinositol 3-kinase inhibitor activity (GO:0141039)positive regulation of cell migration (GO:0030335)positive regulation of pseudopodium assembly (GO:0031274)protein binding (GO:0005515)recycling endosome (GO:0055037)recycling endosome (GO:0055037)recycling endosome membrane (GO:0055038)regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)regulation of protein ubiquitination (GO:0031396)retrograde transport, endosome to Golgi (GO:0042147)retrograde transport, endosome to Golgi (GO:0042147)retrograde transport, endosome to Golgi (GO:0042147)ubiquitin protein ligase binding (GO:0031625)

Expression (TPM)