Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TMEM255B. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TMEM255B upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TMEM255B, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr13:113,489,310–113,491,886 | 268.3 kb | Distal (>10kb) Multiome | 791 | |
| chr13:113,584,313–113,585,542 | 174.6 kb | Distal (>10kb) Multiome | 559 | |
| chr13:113,652,944–113,653,751 | 105.9 kb | Distal (>10kb) Multiome | 168 | |
| chr13:113,758,648–113,759,690 | 29 bp | At TSS Multiome | 428 | |
| chr13:113,860,084–113,861,280 | 101.5 kb | Distal (>10kb) Multiome | 327 |
Genomic view of the TMEM255B locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.