Located in sperm flagellum. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TEX55. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TEX55 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TEX55, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr3:119,034,159–119,035,267 | 111.4 kb | Distal (>10kb) Multiome | 570 | |
| chr3:119,145,272–119,146,225 | at TSS | At TSS | 170 | |
| chr3:119,206,295–119,207,798 | 60.8 kb | Distal (>10kb) Multiome | 256 | |
| chr3:119,210,998–119,211,738 | 65.3 kb | Distal (>10kb) Multiome | 234 | |
| chr3:119,240,068–119,241,279 | 94.7 kb | Distal (>10kb) Multiome | 820 | |
| chr3:119,241,393–119,241,941 | 95.6 kb | Distal (>10kb) Multiome | 393 | |
| chr3:119,293,740–119,295,412 | 148.0 kb | Distal (>10kb) Multiome | 540 | |
| chr3:119,322,394–119,324,118 | 176.8 kb | Distal (>10kb) Multiome | 824 | |
| chr3:119,349,421–119,349,961 | 203.5 kb | Distal (>10kb) Multiome | 181 | |
| chr3:119,417,868–119,418,544 | 272.2 kb | Distal (>10kb) Multiome | 156 | |
| chr3:119,676,820–119,677,853 | 531.2 kb | Distal (>10kb) Multiome HiCAR | 778 |
Genomic view of the TEX55 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.