Enables enzyme binding activity and glycogen binding activity. Involved in glycophagy and intracellular transport. Located in T-tubule; endoplasmic reticulum; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for STBD1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = STBD1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of STBD1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr4:76,147,405–76,148,870 | 158.2 kb | Distal (>10kb) Multiome | 1076 | |
| chr4:76,212,911–76,214,625 | 92.9 kb | Distal (>10kb) Multiome HiCAR | 798 | |
| chr4:76,251,398–76,252,255 | 55.0 kb | Distal (>10kb) Multiome | 710 | |
| chr4:76,305,965–76,307,583 | 105 bp | At TSS Multiome | 793 | |
| chr4:76,308,551–76,308,966 | 1.8 kb | Proximal (<10kb) | 219 | |
| chr4:76,585,845–76,586,672 | 279.5 kb | Distal (>10kb) Multiome | 423 |
Genomic view of the STBD1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.