Predicted to enable zinc ion binding activity. Predicted to be involved in RNA splicing. Located in cytosol and nucleoplasm. Part of U12-type spliceosomal complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SNRNP48. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNRNP48 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNRNP48, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr6:7,312,560–7,313,754 | 277.0 kb | Distal (>10kb) Multiome | 1075 | |
| chr6:7,347,359–7,348,352 | 242.4 kb | Distal (>10kb) Multiome | 256 | |
| chr6:7,389,283–7,390,343 | 200.4 kb | Distal (>10kb) Multiome HiCAR | 1040 | |
| chr6:7,541,127–7,543,319 | 48.7 kb | Distal (>10kb) Multiome | 970 | |
| chr6:7,548,319–7,549,268 | 41.5 kb | Distal (>10kb) Multiome | 504 | |
| chr6:7,589,842–7,590,956 | 48 bp | At TSS Multiome | 877 | |
| chr6:7,615,396–7,616,491 | 25.8 kb | Distal (>10kb) Multiome | 297 | |
| chr6:7,672,770–7,673,478 | 83.1 kb | Distal (>10kb) Multiome | 337 | |
| chr6:7,725,533–7,728,906 | 135.9 kb | Distal (>10kb) Multiome | 639 |
Genomic view of the SNRNP48 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.