Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SNORA73B. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNORA73B upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNORA73B, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:28,505,412–28,506,885 | 1.7 kb | Proximal (<10kb) | 969 | |
| chr1:28,507,602–28,508,074 | 483 bp | At TSS | 236 | |
| chr1:28,508,380–28,508,689 | at TSS | At TSS | 222 | |
| chr1:28,510,330–28,511,247 | 1.8 kb | Proximal (<10kb) | 617 | |
| chr1:28,511,458–28,511,980 | 2.9 kb | Proximal (<10kb) | 217 | |
| chr1:28,513,136–28,516,505 | 4.6 kb | Proximal (<10kb) | 461 | |
| chr1:28,517,302–28,519,364 | 8.7 kb | Proximal (<10kb) | 927 |
Genomic view of the SNORA73B locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.