Predicted to be involved in several processes, including cellular response to fatty acid; macrophage activation; and tyrosine phosphorylation of STAT protein. Predicted to be located in nucleolus. Implicated in lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SNHG20. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNHG20 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNHG20, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr17:76,868,004–76,869,024 | 220.3 kb | Distal (>10kb) Multiome | 481 | |
| chr17:76,968,327–76,970,292 | 119.5 kb | Distal (>10kb) Multiome | 512 | |
| chr17:77,086,574–77,086,808 | 1.9 kb | Proximal (<10kb) | 399 | |
| chr17:77,088,470–77,089,058 | 34 bp | At TSS Multiome | 979 | |
| chr17:77,139,981–77,141,779 | 52.0 kb | Distal (>10kb) Multiome | 1027 | |
| chr17:77,246,721–77,247,535 | 158.5 kb | Distal (>10kb) Multiome | 586 | |
| chr17:77,279,760–77,282,164 | 192.6 kb | Distal (>10kb) Multiome | 914 | |
| chr17:77,372,046–77,374,884 | 284.4 kb | Distal (>10kb) Multiome | 945 |
Genomic view of the SNHG20 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.