Enables sodium:sulfate symporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SLC13A4. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC13A4 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC13A4, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr7:135,509,171–135,510,811 | 218.0 kb | Distal (>10kb) Multiome | 903 | |
| chr7:135,557,472–135,558,749 | 170.3 kb | Distal (>10kb) Multiome | 957 | |
| chr7:135,562,644–135,563,104 | 165.2 kb | Distal (>10kb) Multiome | 115 | |
| chr7:135,661,395–135,663,087 | 65.8 kb | Distal (>10kb) Multiome | 1079 | |
| chr7:135,727,964–135,728,827 | 132 bp | At TSS Multiome | 212 | |
| chr7:135,862,755–135,863,627 | 135.0 kb | Distal (>10kb) Multiome | 120 | |
| chr7:135,976,606–135,977,924 | 249.1 kb | Distal (>10kb) Multiome | 832 | |
| chr7:137,003,099–137,004,392 | 1275.6 kb | Distal (>10kb) Multiome HiCAR | 147 |
Genomic view of the SLC13A4 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.