Involved in mitophagy. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for RIMOC1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = RIMOC1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of RIMOC1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:41,868,976–41,871,057 | 33.9 kb | Distal (>10kb) Multiome | 726 | |
| chr5:41,903,698–41,904,758 | 146 bp | At TSS Multiome | 1018 | |
| chr5:41,924,742–41,926,001 | 20.9 kb | Distal (>10kb) Multiome | 1012 | |
| chr5:42,811,575–42,812,593 | 907.8 kb | Distal (>10kb) Multiome HiCAR | 702 | |
| chr5:42,813,381–42,813,999 | 909.4 kb | Distal (>10kb) Multiome HiCAR | 122 | |
| chr5:42,893,601–42,894,516 | 989.7 kb | Distal (>10kb) Multiome HiCAR | 155 |
Genomic view of the RIMOC1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.