Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in endoplasmic reticulum; nuclear membrane; and nucleolus. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for RBMX2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = RBMX2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of RBMX2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chrX:130,120,389–130,121,207 | 281.1 kb | Distal (>10kb) Multiome | 517 | |
| chrX:130,165,452–130,166,368 | 236.1 kb | Distal (>10kb) Multiome | 754 | |
| chrX:130,170,895–130,171,447 | 230.9 kb | Distal (>10kb) Multiome | 203 | |
| chrX:130,268,321–130,269,066 | 133.2 kb | Distal (>10kb) Multiome | 738 | |
| chrX:130,339,460–130,340,239 | 62.1 kb | Distal (>10kb) Multiome | 548 | |
| chrX:130,401,606–130,402,359 | at TSS | At TSS | 427 | |
| chrX:130,902,558–130,903,576 | 501.2 kb | Distal (>10kb) Multiome HiCAR | 672 |
Genomic view of the RBMX2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.