RAB29

RAB29, member RAS oncogene family | RAB7L, RAB7L1

Enables several functions, including dynein complex binding activity; guanyl ribonucleotide binding activity; and kinesin binding activity. Involved in several processes, including positive regulation of T cell receptor signaling pathway; positive regulation of receptor recycling; and retrograde transport, endosome to Golgi. Located in several cellular components, including Golgi apparatus; endosome; and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 60 terms

G protein activity (GO:0003925)G protein activity (GO:0003925)GDP binding (GO:0019003)GDP binding (GO:0019003)GTP binding (GO:0005525)GTP binding (GO:0005525)GTPase activity (GO:0003924)GTPase activity (GO:0003924)GTPase activity (GO:0003924)Golgi apparatus (GO:0005794)Golgi apparatus (GO:0005794)Golgi membrane (GO:0000139)Golgi organization (GO:0007030)T cell activation (GO:0042110)cellular detoxification (GO:1990748)cis-Golgi network (GO:0005801)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytoplasmic vesicle (GO:0031410)cytoskeleton (GO:0005856)cytosol (GO:0005829)dynein complex binding (GO:0070840)early endosome (GO:0005769)endomembrane system (GO:0012505)endoplasmic reticulum to Golgi vesicle-mediated transport (GO:0006888)extracellular exosome (GO:0070062)host-mediated perturbation of viral process (GO:0044788)intracellular protein transport (GO:0006886)intracellular vesicle (GO:0097708)kinase activator activity (GO:0019209)kinesin binding (GO:0019894)melanosome (GO:0042470)melanosome organization (GO:0032438)mitochondrion (GO:0005739)mitochondrion organization (GO:0007005)mitochondrion organization (GO:0007005)negative regulation of neuron projection development (GO:0010977)perinuclear region of cytoplasm (GO:0048471)plasma membrane (GO:0005886)positive regulation of T cell receptor signaling pathway (GO:0050862)positive regulation of intracellular protein transport (GO:0090316)positive regulation of receptor recycling (GO:0001921)protein binding (GO:0005515)protein localization to ciliary membrane (GO:1903441)protein localization to membrane (GO:0072657)protein localization to membrane (GO:0072657)recycling endosome (GO:0055037)regulation of motile cilium assembly (GO:1905503)regulation of retrograde transport, endosome to Golgi (GO:1905279)response to bacterium (GO:0009617)retrograde transport, endosome to Golgi (GO:0042147)small GTPase binding (GO:0031267)synapse assembly (GO:0007416)trans-Golgi network (GO:0005802)trans-Golgi network (GO:0005802)trans-Golgi network (GO:0005802)vacuole (GO:0005773)vacuole (GO:0005773)vesicle (GO:0031982)vesicle-mediated transport (GO:0016192)

Expression (TPM)

TFs regulating RAB29 0 TFs

Transcription factors with Perturb-seq knockdown data for RAB29. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = RAB29 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to RAB29

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of RAB29, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr1:205,485,282–205,485,813	289.9 kb	Distal (>10kb) Multiome	590
chr1:205,504,221–205,505,625	270.8 kb	Distal (>10kb) Multiome	631
chr1:205,528,647–205,529,482	246.3 kb	Distal (>10kb) Multiome	390
chr1:205,543,280–205,544,028	231.8 kb	Distal (>10kb) Multiome	371
chr1:205,591,729–205,592,393	183.4 kb	Distal (>10kb) Multiome	624
chr1:205,631,034–205,632,587	143.5 kb	Distal (>10kb) Multiome	1054
chr1:205,679,697–205,680,913	94.9 kb	Distal (>10kb) Multiome	568
chr1:205,748,908–205,750,848	25.9 kb	Distal (>10kb) Multiome	1074
chr1:205,774,834–205,775,616	39 bp	At TSS Multiome	637
chr1:205,812,462–205,814,100	37.9 kb	Distal (>10kb) Multiome	693
chr1:205,849,914–205,850,368	74.7 kb	Distal (>10kb) Multiome	143

Genome Browser

Genomic view of the RAB29 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.