PLCD4

phospholipase C delta 4

This gene encodes a member of the delta class of phospholipase C enzymes. Phospholipase C enzymes play a critical role in many cellular processes by hydrolyzing phosphatidylinositol 4,5-bisphosphate into two intracellular second messengers, inositol 1,4,5-trisphosphate and diacylglycerol. Expression of this gene may be a marker for cancer. [provided by RefSeq, Jan 2011]

Biological processes 20 terms

G-protein alpha-subunit binding (GO:0001965)calcium ion binding (GO:0005509)cytoplasm (GO:0005737)cytoplasmic side of plasma membrane (GO:0009898)cytosol (GO:0005829)endoplasmic reticulum (GO:0005783)endoplasmic reticulum membrane (GO:0005789)guanyl-nucleotide exchange factor activity (GO:0005085)intracellular signal transduction (GO:0035556)lipid metabolic process (GO:0006629)membrane (GO:0016020)nucleus (GO:0005634)phosphatidylinositol phospholipase C activity (GO:0120548)phosphatidylinositol-4,5-bisphosphate phospholipase C activity (GO:0004435)phosphatidylinositol-4,5-bisphosphate phospholipase C activity (GO:0004435)phosphoric diester hydrolase activity (GO:0008081)plasma membrane (GO:0005886)protein binding (GO:0005515)signal transduction (GO:0007165)small GTPase-mediated signal transduction (GO:0007264)

Expression (TPM)