Predicted to enable magnesium ion binding activity. Predicted to be involved in acyl-CoA metabolic process and coenzyme A catabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for NUDT19. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = NUDT19 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of NUDT19, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:32,403,163–32,403,921 | 288.3 kb | Distal (>10kb) Multiome | 151 | |
| chr19:32,405,092–32,406,553 | 286.0 kb | Distal (>10kb) Multiome | 914 | |
| chr19:32,580,669–32,581,896 | 110.7 kb | Distal (>10kb) Multiome | 774 | |
| chr19:32,674,338–32,676,683 | 16.5 kb | Distal (>10kb) Multiome | 792 | |
| chr19:32,691,659–32,692,482 | 175 bp | At TSS Multiome | 839 | |
| chr19:32,701,845–32,702,627 | 10.4 kb | Distal (>10kb) Multiome | 257 | |
| chr19:32,706,824–32,707,422 | 15.3 kb | Distal (>10kb) Multiome | 106 | |
| chr19:32,971,721–32,972,560 | 280.3 kb | Distal (>10kb) Multiome | 796 |
Genomic view of the NUDT19 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.