NEUROD2
neuronal differentiation 2 | NDRF, bHLHa1

This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. [provided by RefSeq, Jul 2008]

Biological processes 46 terms
DNA binding (GO:0003677)DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228)DNA-binding transcription factor activity (GO:0003700)DNA-binding transcription factor activity (GO:0003700)DNA-binding transcription factor activity (GO:0003700)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)E-box binding (GO:0070888)E-box binding (GO:0070888)E-box binding (GO:0070888)RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)axon development (GO:0061564)cellular response to calcium ion (GO:0071277)cellular response to calcium ion (GO:0071277)cellular response to electrical stimulus (GO:0071257)cellular response to electrical stimulus (GO:0071257)cerebellar cortex development (GO:0021695)cerebellar cortex development (GO:0021695)chromatin (GO:0000785)negative regulation of synapse maturation (GO:2000297)negative regulation of synapse maturation (GO:2000297)nervous system development (GO:0007399)nervous system development (GO:0007399)nucleus (GO:0005634)nucleus (GO:0005634)nucleus (GO:0005634)positive regulation of calcium-mediated signaling (GO:0050850)positive regulation of calcium-mediated signaling (GO:0050850)positive regulation of neuron differentiation (GO:0045666)positive regulation of neuron differentiation (GO:0045666)positive regulation of synapse maturation (GO:0090129)positive regulation of synapse maturation (GO:0090129)positive regulation of synaptic plasticity (GO:0031915)positive regulation of synaptic plasticity (GO:0031915)positive regulation of transcription by RNA polymerase II (GO:0045944)positive regulation of transcription by RNA polymerase II (GO:0045944)protein dimerization activity (GO:0046983)protein heterodimerization activity (GO:0046982)protein heterodimerization activity (GO:0046982)protein ubiquitination (GO:0016567)protein ubiquitination (GO:0016567)regulation of DNA-templated transcription (GO:0006355)regulation of transcription by RNA polymerase II (GO:0006357)sensory organ development (GO:0007423)sequence-specific double-stranded DNA binding (GO:1990837)sequence-specific double-stranded DNA binding (GO:1990837)
Expression (TPM)
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