NDP

norrin cystine knot growth factor NDP | norrin, EVR2

This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy. [provided by RefSeq, Feb 2009]

Biological processes 25 terms

Norrin signaling pathway (GO:0110135)Norrin signaling pathway (GO:0110135)Norrin signaling pathway (GO:0110135)Wnt signaling pathway (GO:0016055)cell surface (GO:0009986)cytokine activity (GO:0005125)cytokine activity (GO:0005125)cytokine activity (GO:0005125)decidualization (GO:0046697)extracellular matrix-cell signaling (GO:0035426)extracellular region (GO:0005576)extracellular region (GO:0005576)frizzled binding (GO:0005109)frizzled binding (GO:0005109)frizzled binding (GO:0005109)nervous system development (GO:0007399)nervous system development (GO:0007399)positive regulation of DNA-templated transcription (GO:0045893)positive regulation of DNA-templated transcription (GO:0045893)positive regulation of transcription by RNA polymerase II (GO:0045944)positive regulation of transcription by RNA polymerase II (GO:0045944)protein binding (GO:0005515)protein homodimerization activity (GO:0042803)vacuole organization (GO:0007033)visual perception (GO:0007601)

Expression (TPM)