Transcription factors with Perturb-seq knockdown data for MIR3936HG. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MIR3936HG upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MIR3936HG, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:132,226,810–132,228,575 | 141.7 kb | Distal (>10kb) Multiome | 725 | |
| chr5:132,256,858–132,258,371 | 112.1 kb | Distal (>10kb) Multiome | 338 | |
| chr5:132,293,061–132,295,661 | 75.5 kb | Distal (>10kb) Multiome | 1053 | |
| chr5:132,369,150–132,370,578 | 71 bp | At TSS Multiome | 819 | |
| chr5:132,410,330–132,411,433 | 41.3 kb | Distal (>10kb) Multiome | 815 | |
| chr5:132,419,541–132,419,986 | 50.2 kb | Distal (>10kb) Multiome | 481 | |
| chr5:132,426,660–132,427,851 | 57.4 kb | Distal (>10kb) Multiome | 540 | |
| chr5:132,489,909–132,492,004 | 121.2 kb | Distal (>10kb) Multiome | 899 | |
| chr5:132,495,550–132,497,614 | 126.8 kb | Distal (>10kb) Multiome | 946 | |
| chr5:132,526,534–132,527,026 | 157.2 kb | Distal (>10kb) Multiome | 329 | |
| chr5:132,556,575–132,557,723 | 187.3 kb | Distal (>10kb) Multiome | 1071 | |
| chr5:132,655,819–132,656,736 | 286.6 kb | Distal (>10kb) Multiome | 235 |
Genomic view of the MIR3936HG locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.