Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for MFSD9. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MFSD9 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MFSD9, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr2:102,618,817–102,620,848 | 117.3 kb | Distal (>10kb) Multiome | 562 | |
| chr2:102,704,415–102,705,118 | 32.1 kb | Distal (>10kb) Multiome | 110 | |
| chr2:102,735,444–102,735,664 | 1.2 kb | Proximal (<10kb) | 95 | |
| chr2:102,735,780–102,737,390 | 29 bp | At TSS Multiome | 858 | |
| chr2:102,743,829–102,744,160 | 7.0 kb | Proximal (<10kb) | 10 |
Genomic view of the MFSD9 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.