The protein encoded by this gene belongs to the MAP7 (microtubule-associated protein 7) family. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Mar 2010]
Transcription factors with Perturb-seq knockdown data for MAP7D3. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MAP7D3 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MAP7D3, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chrX:135,973,479–135,974,209 | 277.2 kb | Distal (>10kb) Multiome | 624 | |
| chrX:135,985,105–135,985,952 | 265.9 kb | Distal (>10kb) Multiome | 442 | |
| chrX:136,146,916–136,147,890 | 104.0 kb | Distal (>10kb) Multiome | 231 | |
| chrX:136,250,770–136,251,801 | 21 bp | At TSS Multiome | 399 | |
| chrX:136,496,533–136,498,003 | 245.8 kb | Distal (>10kb) Multiome | 629 |
Genomic view of the MAP7D3 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.