LRRC47

leucine rich repeat containing 47 | KIAA1185, RP1-286D6.3

Enables RNA binding activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 5 terms

RNA binding (GO:0003723)RNA binding (GO:0003723)phenylalanine-tRNA ligase activity (GO:0004826)phenylalanyl-tRNA aminoacylation (GO:0006432)protein binding (GO:0005515)

Expression (TPM)

TFs regulating LRRC47 0 TFs

Transcription factors with Perturb-seq knockdown data for LRRC47. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = LRRC47 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to LRRC47

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of LRRC47, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr1:3,530,504–3,532,073	265.0 kb	Distal (>10kb) Multiome	442
chr1:3,610,667–3,612,281	184.9 kb	Distal (>10kb) Multiome	361
chr1:3,624,289–3,625,883	171.6 kb	Distal (>10kb) Multiome	814
chr1:3,649,785–3,650,304	146.4 kb	Distal (>10kb) Multiome	620
chr1:3,651,921–3,653,136	143.7 kb	Distal (>10kb) Multiome	369
chr1:3,746,744–3,747,607	49.1 kb	Distal (>10kb) Multiome	523
chr1:3,771,515–3,773,363	23.9 kb	Distal (>10kb) Multiome	733
chr1:3,793,373–3,793,897	2.8 kb	Proximal (<10kb) Multiome	182
chr1:3,795,866–3,796,907	24 bp	At TSS Multiome	835
chr1:3,856,527–3,858,218	60.8 kb	Distal (>10kb) Multiome	815
chr1:3,899,608–3,901,755	104.9 kb	Distal (>10kb) Multiome	1026
chr1:3,910,694–3,911,367	114.5 kb	Distal (>10kb) Multiome	321

Genome Browser

Genomic view of the LRRC47 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.