LMTK3
lemur tyrosine kinase 3 | AATYK3, KIAA1883, LMR3, PPP1R101, TYKLM3

Predicted to enable protein kinase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in Golgi membrane; axon; and dendrite. [provided by Alliance of Genome Resources, Apr 2025]

Biological processes 12 terms
Expression (TPM)
LMTK3 — as a Regulated Gene

TFs regulating LMTK3 0 TFs

Transcription factors with Perturb-seq knockdown data for LMTK3. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = LMTK3 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to LMTK3

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of LMTK3, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr19:48,203,709–48,204,551 307.8 kb Distal (>10kb) Multiome 741
chr19:48,271,198–48,272,050 240.3 kb Distal (>10kb) Multiome 562
chr19:48,290,181–48,291,716 221.0 kb Distal (>10kb) Multiome 666
chr19:48,320,062–48,322,328 190.3 kb Distal (>10kb) Multiome 826
chr19:48,330,094–48,330,787 181.5 kb Distal (>10kb) Multiome 460
chr19:48,332,701–48,333,506 178.9 kb Distal (>10kb) Multiome 615
chr19:48,333,584–48,334,372 177.7 kb Distal (>10kb) Multiome 554
chr19:48,363,062–48,364,710 147.6 kb Distal (>10kb) Multiome 940
chr19:48,390,663–48,391,935 120.2 kb Distal (>10kb) Multiome 816
chr19:48,397,916–48,399,301 113.0 kb Distal (>10kb) Multiome 619
chr19:48,399,411–48,400,900 111.2 kb Distal (>10kb) Multiome 548
chr19:48,414,121–48,416,085 96.3 kb Distal (>10kb) Multiome 298
chr19:48,445,379–48,446,456 65.9 kb Distal (>10kb) Multiome 845
chr19:48,468,758–48,470,027 42.7 kb Distal (>10kb) Multiome 860
chr19:48,490,661–48,494,449 20.5 kb Distal (>10kb) Multiome 633
chr19:48,500,898–48,503,050 9.8 kb Proximal (<10kb) Multiome 656
chr19:48,510,624–48,511,212 1.1 kb Proximal (<10kb) Multiome 268
chr19:48,513,480–48,514,294 2.1 kb Proximal (<10kb) Multiome 585
chr19:48,614,318–48,615,255 103.0 kb Distal (>10kb) Multiome 524
chr19:48,618,726–48,619,869 107.5 kb Distal (>10kb) Multiome 1012
chr19:48,623,839–48,624,688 112.4 kb Distal (>10kb) Multiome 529
chr19:48,629,369–48,631,306 118.2 kb Distal (>10kb) Multiome 402
chr19:48,634,242–48,636,244 123.9 kb Distal (>10kb) Multiome 868
chr19:48,636,802–48,639,603 126.6 kb Distal (>10kb) Multiome 956
chr19:48,645,454–48,647,163 134.7 kb Distal (>10kb) Multiome 750
chr19:48,675,421–48,675,873 163.7 kb Distal (>10kb) Multiome 415
chr19:48,695,830–48,697,033 184.3 kb Distal (>10kb) Multiome 253
chr19:48,713,646–48,714,846 202.5 kb Distal (>10kb) Multiome 719
chr19:48,716,551–48,717,038 205.1 kb Distal (>10kb) Multiome 241
chr19:48,720,420–48,721,301 209.1 kb Distal (>10kb) Multiome 689
chr19:48,735,001–48,735,602 223.4 kb Distal (>10kb) Multiome 161
chr19:48,738,441–48,739,812 227.1 kb Distal (>10kb) Multiome 743
chr19:48,741,194–48,741,939 229.7 kb Distal (>10kb) Multiome 350
chr19:48,746,830–48,747,395 235.3 kb Distal (>10kb) Multiome 402
chr19:48,752,314–48,753,547 241.1 kb Distal (>10kb) Multiome 545
chr19:48,795,165–48,795,736 283.7 kb Distal (>10kb) Multiome 724
chr19:48,806,734–48,807,478 295.1 kb Distal (>10kb) Multiome 452
chr19:48,810,774–48,811,494 299.2 kb Distal (>10kb) Multiome 662

Genome Browser

Genomic view of the LMTK3 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr19:48,193,709 – 48,821,494
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq