Transcription factors with Perturb-seq knockdown data for LINC02542. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = LINC02542 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of LINC02542, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr6:82,097,842–82,098,423 | 3.4 kb | Proximal (<10kb) | 107 | |
| chr6:82,101,441–82,102,050 | at TSS | At TSS | 207 | |
| chr6:82,160,004–82,160,380 | 374 bp | At TSS | 13 | |
| chr6:82,160,515–82,161,110 | at TSS | At TSS | 66 | |
| chr6:82,164,092–82,164,250 | 3.3 kb | Proximal (<10kb) | 7 | |
| chr6:82,164,362–82,164,489 | 3.6 kb | Proximal (<10kb) | 4 | |
| chr6:82,246,942–82,248,798 | 146.0 kb | Distal (>10kb) Multiome | 957 | |
| chr6:82,256,786–82,258,089 | 155.5 kb | Distal (>10kb) Multiome | 171 | |
| chr6:82,363,222–82,366,030 | 262.0 kb | Distal (>10kb) Multiome | 857 |
Genomic view of the LINC02542 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.