LGALS9
galectin 9 | LGALS9A

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Biological processes 75 terms
ERK1 and ERK2 cascade (GO:0070371)NK T cell activation (GO:0051132)carbohydrate binding (GO:0030246)carbohydrate binding (GO:0030246)carbohydrate binding (GO:0030246)cellular response to type II interferon (GO:0071346)cellular response to virus (GO:0098586)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytosol (GO:0005829)cytosol (GO:0005829)disaccharide binding (GO:0048030)enzyme binding (GO:0019899)extracellular matrix (GO:0031012)extracellular region (GO:0005576)extracellular region (GO:0005576)female pregnancy (GO:0007565)galactose binding (GO:0005534)galactoside binding (GO:0016936)immune response (GO:0006955)inflammatory response (GO:0006954)maternal process involved in female pregnancy (GO:0060135)mature conventional dendritic cell differentiation (GO:0097029)natural killer cell tolerance induction (GO:0002519)negative regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000562)negative regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000562)negative regulation of T-helper 1 type immune response (GO:0002826)negative regulation of activated T cell proliferation (GO:0046007)negative regulation of chemokine production (GO:0032682)negative regulation of gene expression (GO:0010629)negative regulation of gene expression (GO:0010629)negative regulation of mast cell degranulation (GO:0043305)negative regulation of natural killer cell mediated cytotoxicity (GO:0045953)negative regulation of tumor necrosis factor production (GO:0032720)negative regulation of type II interferon production (GO:0032689)negative regulation of type II interferon production (GO:0032689)nucleus (GO:0005634)nucleus (GO:0005634)nucleus (GO:0005634)oligosaccharide binding (GO:0070492)p38MAPK cascade (GO:0038066)positive regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000563)positive regulation of ERK1 and ERK2 cascade (GO:0070374)positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001190)positive regulation of T cell migration (GO:2000406)positive regulation of activated T cell autonomous cell death (GO:0070241)positive regulation of canonical NF-kappaB signal transduction (GO:0043123)positive regulation of dendritic cell apoptotic process (GO:2000670)positive regulation of dendritic cell chemotaxis (GO:2000510)positive regulation of dendritic cell differentiation (GO:2001200)positive regulation of gene expression (GO:0010628)positive regulation of gene expression (GO:0010628)positive regulation of interleukin-1 beta production (GO:0032731)positive regulation of interleukin-10 production (GO:0032733)positive regulation of interleukin-12 production (GO:0032735)positive regulation of interleukin-13 production (GO:0032736)positive regulation of interleukin-4 production (GO:0032753)positive regulation of interleukin-4 production (GO:0032753)positive regulation of interleukin-6 production (GO:0032755)positive regulation of interleukin-8 production (GO:0032757)positive regulation of monocyte chemotactic protein-1 production (GO:0071639)positive regulation of non-canonical NF-kappaB signal transduction (GO:1901224)positive regulation of transforming growth factor beta production (GO:0071636)positive regulation of tumor necrosis factor production (GO:0032760)positive regulation of type II interferon production (GO:0032729)positive regulation of viral entry into host cell (GO:0046598)protein binding (GO:0005515)receptor ligand activity (GO:0048018)regulation of interleukin-4 production (GO:0032673)regulation of interleukin-5 production (GO:0032674)regulation of p38MAPK cascade (GO:1900744)response to interleukin-1 (GO:0070555)response to lipopolysaccharide (GO:0032496)toll-like receptor 2 signaling pathway (GO:0034134)toll-like receptor 4 signaling pathway (GO:0034142)
Expression (TPM)
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