Predicted to enable kinase binding activity and microtubule binding activity. Predicted to be located in Golgi apparatus and membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for JAKMIP3. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = JAKMIP3 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of JAKMIP3, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr10:131,874,962–131,875,578 | 161.5 kb | Distal (>10kb) Multiome | 227 | |
| chr10:131,899,878–131,901,850 | 136.0 kb | Distal (>10kb) Multiome | 732 | |
| chr10:131,929,125–131,929,784 | 107.2 kb | Distal (>10kb) Multiome | 62 | |
| chr10:131,981,341–131,982,864 | 54.6 kb | Distal (>10kb) Multiome | 815 | |
| chr10:131,998,677–131,999,655 | 37.4 kb | Distal (>10kb) Multiome | 271 | |
| chr10:132,001,275–132,002,395 | 35.0 kb | Distal (>10kb) Multiome | 161 | |
| chr10:132,002,510–132,004,411 | 33.1 kb | Distal (>10kb) Multiome | 240 | |
| chr10:132,035,668–132,037,081 | 24 bp | At TSS Multiome | 214 | |
| chr10:132,037,308–132,037,886 | 632 bp | At TSS | 67 | |
| chr10:132,043,711–132,044,133 | 7.0 kb | Proximal (<10kb) | 41 | |
| chr10:132,112,772–132,114,093 | 76.6 kb | Distal (>10kb) Multiome | 141 | |
| chr10:132,163,327–132,163,783 | 126.9 kb | Distal (>10kb) Multiome | 240 | |
| chr10:132,185,497–132,188,136 | 149.0 kb | Distal (>10kb) Multiome | 418 | |
| chr10:132,306,849–132,308,922 | 271.4 kb | Distal (>10kb) Multiome | 613 | |
| chr10:132,331,380–132,332,787 | 295.4 kb | Distal (>10kb) Multiome | 823 |
Genomic view of the JAKMIP3 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.