Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus subcompartment; endoplasmic reticulum; and nuclear envelope. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for GOLT1A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GOLT1A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GOLT1A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:203,795,422–203,796,461 | 418.3 kb | Distal (>10kb) Multiome HiCAR | 784 | |
| chr1:203,861,102–203,862,191 | 352.4 kb | Distal (>10kb) Multiome HiCAR | 1090 | |
| chr1:204,065,124–204,065,934 | 148.5 kb | Distal (>10kb) Multiome | 155 | |
| chr1:204,072,301–204,075,400 | 140.9 kb | Distal (>10kb) Multiome | 828 | |
| chr1:204,078,065–204,078,999 | 135.6 kb | Distal (>10kb) Multiome | 348 | |
| chr1:204,079,587–204,080,941 | 133.5 kb | Distal (>10kb) Multiome | 492 | |
| chr1:204,084,225–204,084,936 | 129.4 kb | Distal (>10kb) Multiome | 439 | |
| chr1:204,108,483–204,109,315 | 105.1 kb | Distal (>10kb) Multiome | 151 | |
| chr1:204,128,928–204,129,568 | 84.7 kb | Distal (>10kb) Multiome | 440 | |
| chr1:204,151,279–204,152,703 | 61.9 kb | Distal (>10kb) Multiome HiCAR | 556 | |
| chr1:204,207,148–204,207,453 | 6.5 kb | Proximal (<10kb) | 328 | |
| chr1:204,213,764–204,214,668 | 240 bp | At TSS Multiome | 702 | |
| chr1:204,350,954–204,351,460 | 137.2 kb | Distal (>10kb) Multiome HiCAR | 138 | |
| chr1:204,377,771–204,378,537 | 164.2 kb | Distal (>10kb) Multiome HiCAR | 593 | |
| chr1:204,411,136–204,412,704 | 197.9 kb | Distal (>10kb) Multiome | 939 | |
| chr1:204,446,280–204,446,835 | 232.5 kb | Distal (>10kb) Multiome | 311 | |
| chr1:204,493,614–204,495,352 | 280.7 kb | Distal (>10kb) Multiome | 876 | |
| chr1:204,506,146–204,507,240 | 292.6 kb | Distal (>10kb) Multiome | 889 | |
| chr1:204,507,371–204,508,288 | 294.0 kb | Distal (>10kb) Multiome | 508 |
Genomic view of the GOLT1A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.