Enables glutamine N-acyltransferase activity. Involved in glutamine metabolic process. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for GLYATL1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GLYATL1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GLYATL1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:58,900,167–58,901,350 | 4.5 kb | Proximal (<10kb) Multiome | 303 | |
| chr11:58,901,576–58,902,237 | 3.2 kb | Proximal (<10kb) | 7 | |
| chr11:58,905,068–58,906,400 | 461 bp | At TSS Multiome | 397 | |
| chr11:58,923,080–58,923,816 | 3.8 kb | Proximal (<10kb) | 195 | |
| chr11:58,923,966–58,925,091 | 2.5 kb | Proximal (<10kb) | 105 | |
| chr11:58,926,958–58,929,011 | 22.2 kb | Distal (>10kb) Multiome | 272 | |
| chr11:58,963,030–58,964,168 | 58.4 kb | Distal (>10kb) Multiome | 243 | |
| chr11:59,058,072–59,058,928 | 153.1 kb | Distal (>10kb) Multiome | 236 | |
| chr11:59,101,879–59,102,715 | 196.9 kb | Distal (>10kb) Multiome | 199 | |
| chr11:59,106,296–59,108,091 | 201.5 kb | Distal (>10kb) Multiome | 495 | |
| chr11:59,142,370–59,143,459 | 237.5 kb | Distal (>10kb) Multiome | 736 | |
| chr11:59,144,606–59,145,343 | 239.5 kb | Distal (>10kb) Multiome | 528 | |
| chr11:59,171,483–59,174,527 | 266.5 kb | Distal (>10kb) Multiome | 865 |
Genomic view of the GLYATL1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.