GJA5
gap junction protein alpha 5 | CX40

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]

Biological processes 75 terms
AV node cell to bundle of His cell communication by electrical coupling (GO:0086053)AV node cell to bundle of His cell communication by electrical coupling (GO:0086053)Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling (GO:0086055)SA node cell to atrial cardiac muscle cell communication by electrical coupling (GO:0086021)angiogenesis (GO:0001525)artery morphogenesis (GO:0048844)artery morphogenesis (GO:0048844)atrial cardiac muscle cell to AV node cell communication by electrical coupling (GO:0086044)atrial cardiac muscle cell to AV node cell communication by electrical coupling (GO:0086044)atrial cardiac muscle cell to AV node cell communication by electrical coupling (GO:0086044)atrial cardiac muscle cell to AV node cell communication by electrical coupling (GO:0086044)atrial septum development (GO:0003283)bundle of His cell to Purkinje myocyte communication by electrical coupling (GO:0086054)bundle of His cell to Purkinje myocyte communication by electrical coupling (GO:0086054)bundle of His cell to Purkinje myocyte communication by electrical coupling (GO:0086054)cardiac conduction system development (GO:0003161)cell communication (GO:0007154)cell communication by chemical coupling (GO:0010643)cell communication by electrical coupling (GO:0010644)cell communication by electrical coupling involved in cardiac conduction (GO:0086064)cell-cell signaling (GO:0007267)connexin binding (GO:0071253)connexin complex (GO:0005922)connexin complex (GO:0005922)connexin complex (GO:0005922)connexin complex (GO:0005922)disordered domain specific binding (GO:0097718)endothelium development (GO:0003158)gap junction (GO:0005921)gap junction (GO:0005921)gap junction assembly (GO:0016264)gap junction assembly (GO:0016264)gap junction channel activity (GO:0005243)gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling (GO:0086077)gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling (GO:0086079)gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling (GO:0086020)gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling (GO:0086076)gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling (GO:0086076)gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling (GO:0086076)gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling (GO:0086078)gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling (GO:0086078)gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling (GO:0086078)gap junction channel activity involved in cardiac conduction electrical coupling (GO:0086075)gap junction channel activity involved in cardiac conduction electrical coupling (GO:0086075)gap junction hemi-channel activity (GO:0055077)heart development (GO:0007507)heart development (GO:0007507)intercalated disc (GO:0014704)intercalated disc (GO:0014704)mitral valve development (GO:0003174)negative regulation of blood pressure (GO:0045776)negative regulation of glomerular filtration (GO:0003105)outflow tract morphogenesis (GO:0003151)plasma membrane (GO:0005886)plasma membrane (GO:0005886)positive regulation of cell communication by chemical coupling (GO:0010652)positive regulation of vasoconstriction (GO:0045907)potassium ion transport (GO:0006813)protein binding (GO:0005515)pulmonary valve formation (GO:0003193)regulation of AV node cell action potential (GO:0098904)regulation of AV node cell action potential (GO:0098904)regulation of Purkinje myocyte action potential (GO:0098906)regulation of atrial cardiac muscle cell action potential (GO:0098910)regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)regulation of bundle of His cell action potential (GO:0098905)regulation of bundle of His cell action potential (GO:0098905)regulation of cardiac muscle contraction (GO:0055117)regulation of cell communication by electrical coupling (GO:0010649)regulation of ventricular cardiac muscle cell membrane depolarization (GO:0060373)regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)transmembrane transport (GO:0055085)vasodilation (GO:0042311)vasomotion (GO:1990029)ventricular septum development (GO:0003281)
Expression (TPM)