Enables polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via serine and protein O-linked glycosylation via threonine. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for GALNT16. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GALNT16 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GALNT16, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr14:68,977,829–68,980,593 | 280.6 kb | Distal (>10kb) Multiome | 919 | |
| chr14:69,151,308–69,153,780 | 108.3 kb | Distal (>10kb) Multiome | 936 | |
| chr14:69,191,332–69,192,132 | 68.3 kb | Distal (>10kb) Multiome | 977 | |
| chr14:69,259,475–69,261,593 | 1.3 kb | Proximal (<10kb) Multiome | 477 | |
| chr14:69,397,842–69,399,035 | 138.6 kb | Distal (>10kb) Multiome | 926 | |
| chr14:69,483,950–69,485,210 | 224.7 kb | Distal (>10kb) Multiome | 334 | |
| chr14:69,547,663–69,548,492 | 288.1 kb | Distal (>10kb) Multiome | 213 |
Genomic view of the GALNT16 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.