Predicted to act upstream of or within apoptotic process and spermatogenesis. Located in sperm flagellum. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FHAD1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FHAD1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FHAD1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:15,152,399–15,154,344 | 93.5 kb | Distal (>10kb) Multiome | 772 | |
| chr1:15,196,898–15,197,476 | 50.0 kb | Distal (>10kb) Multiome | 173 | |
| chr1:15,246,891–15,247,752 | 20 bp | At TSS Multiome | 362 | |
| chr1:15,409,150–15,410,227 | 162.5 kb | Distal (>10kb) Multiome | 618 | |
| chr1:15,523,864–15,525,570 | 277.3 kb | Distal (>10kb) Multiome | 674 | |
| chr1:15,526,118–15,527,442 | 279.5 kb | Distal (>10kb) Multiome | 899 |
Genomic view of the FHAD1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.