FGD3

FYVE, RhoGEF and PH domain containing 3 | FLJ00004, ZFYVE5

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization; filopodium assembly; and regulation of cell shape. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 23 terms

Golgi apparatus (GO:0005794)actin cytoskeleton organization (GO:0030036)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytoplasm (GO:0005737)cytoskeleton (GO:0005856)cytoskeleton organization (GO:0007010)cytoskeleton organization (GO:0007010)cytosol (GO:0005829)filopodium assembly (GO:0046847)filopodium assembly (GO:0046847)guanyl-nucleotide exchange factor activity (GO:0005085)guanyl-nucleotide exchange factor activity (GO:0005085)guanyl-nucleotide exchange factor activity (GO:0005085)guanyl-nucleotide exchange factor activity (GO:0005085)lamellipodium (GO:0030027)metal ion binding (GO:0046872)regulation of GTPase activity (GO:0043087)regulation of cell shape (GO:0008360)regulation of small GTPase mediated signal transduction (GO:0051056)regulation of small GTPase mediated signal transduction (GO:0051056)ruffle (GO:0001726)small GTPase binding (GO:0031267)

Expression (TPM)