FDXR
ferredoxin reductase | ADR, AR, ADXR
FDXR — as a Regulated Gene

TFs regulating FDXR 0 TFs

Transcription factors with Perturb-seq knockdown data for FDXR. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FDXR upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to FDXR

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FDXR, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr17:74,642,311–74,642,966 230.1 kb Distal (>10kb) Multiome 119
chr17:74,643,823–74,644,224 228.8 kb Distal (>10kb) Multiome 17
chr17:74,671,047–74,671,700 201.6 kb Distal (>10kb) Multiome 938
chr17:74,736,296–74,738,156 135.6 kb Distal (>10kb) Multiome 797
chr17:74,744,666–74,745,585 128.2 kb Distal (>10kb) Multiome 580
chr17:74,745,827–74,747,102 126.4 kb Distal (>10kb) Multiome 213
chr17:74,748,109–74,749,683 124.5 kb Distal (>10kb) Multiome 915
chr17:74,775,871–74,776,940 96.6 kb Distal (>10kb) Multiome 798
chr17:74,842,511–74,843,541 30.0 kb Distal (>10kb) Multiome 412
chr17:74,852,259–74,853,211 20.4 kb Distal (>10kb) Multiome 435
chr17:74,864,803–74,865,168 7.8 kb Proximal (<10kb) 262
chr17:74,872,506–74,873,926 153 bp At TSS Multiome 1008
chr17:74,893,600–74,894,183 20.8 kb Distal (>10kb) Multiome 189
chr17:74,923,198–74,923,804 50.6 kb Distal (>10kb) Multiome 543
chr17:74,972,019–74,973,116 99.7 kb Distal (>10kb) Multiome 607
chr17:74,982,006–74,982,936 109.4 kb Distal (>10kb) Multiome 952
chr17:74,987,081–74,988,770 114.6 kb Distal (>10kb) Multiome 702
chr17:75,012,158–75,013,285 139.7 kb Distal (>10kb) Multiome 1058
chr17:75,033,550–75,035,757 162.1 kb Distal (>10kb) Multiome 1228
chr17:75,046,451–75,047,855 174.1 kb Distal (>10kb) Multiome 961
chr17:75,087,344–75,088,429 214.8 kb Distal (>10kb) Multiome 717
chr17:75,089,013–75,089,866 216.4 kb Distal (>10kb) Multiome 406
chr17:75,104,838–75,106,094 232.7 kb Distal (>10kb) Multiome 454
chr17:75,109,401–75,110,734 236.9 kb Distal (>10kb) Multiome 762
chr17:75,113,757–75,114,535 241.2 kb Distal (>10kb) Multiome 585
chr17:75,130,577–75,132,090 258.7 kb Distal (>10kb) Multiome 990
chr17:75,153,354–75,155,273 281.6 kb Distal (>10kb) Multiome 993

Genome Browser

Genomic view of the FDXR locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr17:74,632,311 – 75,165,273
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq