FCER2

Fc epsilon receptor II | CD23, CLEC4J, FCErII, FcepsilonRII, CD23A, FCE2

The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Biological processes 21 terms

B cell antigen processing and presentation (GO:0002450)Fc receptor-mediated immune complex endocytosis (GO:0160006)Fc-epsilon receptor signaling pathway (GO:0038095)Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)IgE binding (GO:0019863)carbohydrate binding (GO:0030246)defense response to bacterium (GO:0042742)external side of plasma membrane (GO:0009897)extracellular exosome (GO:0070062)extracellular region (GO:0005576)immune response (GO:0006955)integrin binding (GO:0005178)low-affinity IgE receptor activity (GO:0019769)macrophage activation (GO:0042116)pattern recognition receptor activity (GO:0038187)plasma membrane (GO:0005886)plasma membrane (GO:0005886)plasma membrane (GO:0005886)positive regulation of gene expression (GO:0010628)protease binding (GO:0002020)protein binding (GO:0005515)

Expression (TPM)