TFs regulating FAM200C 0 TFs

Transcription factors with Perturb-seq knockdown data for FAM200C. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FAM200C upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to FAM200C

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FAM200C, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr5:160,118,295–160,120,363	280.4 kb	Distal (>10kb) Multiome	890
chr5:160,133,074–160,134,351	266.4 kb	Distal (>10kb) Multiome	270
chr5:160,159,956–160,160,873	239.8 kb	Distal (>10kb) Multiome	276
chr5:160,165,122–160,166,166	234.2 kb	Distal (>10kb) Multiome	537
chr5:160,188,095–160,189,161	211.5 kb	Distal (>10kb) Multiome	472
chr5:160,199,034–160,200,016	200.5 kb	Distal (>10kb) Multiome	455
chr5:160,287,012–160,288,061	112.4 kb	Distal (>10kb) Multiome	461
chr5:160,311,564–160,313,046	87.5 kb	Distal (>10kb) Multiome	576
chr5:160,344,991–160,345,682	54.7 kb	Distal (>10kb) Multiome	420
chr5:160,399,366–160,400,211	93 bp	At TSS Multiome	808
chr5:160,418,768–160,419,557	19.1 kb	Distal (>10kb) Multiome	703
chr5:160,421,652–160,422,209	21.8 kb	Distal (>10kb) Multiome	576
chr5:160,438,451–160,439,591	39.1 kb	Distal (>10kb) Multiome	556

Genome Browser

Genomic view of the FAM200C locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.