Predicted to enable methylated histone binding activity. Located in nuclear envelope. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for FAM156A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FAM156A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FAM156A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chrX:51,332,185–51,333,283 | 1662.8 kb | Distal (>10kb) Multiome HiCAR | 171 | |
| chrX:52,920,527–52,921,722 | 74.4 kb | Distal (>10kb) Multiome | 769 | |
| chrX:52,934,457–52,935,577 | 60.5 kb | Distal (>10kb) Multiome | 844 | |
| chrX:52,995,188–52,996,036 | 202 bp | At TSS Multiome | 504 | |
| chrX:53,048,205–53,048,827 | 53.1 kb | Distal (>10kb) Multiome | 184 | |
| chrX:53,081,783–53,082,862 | 86.7 kb | Distal (>10kb) Multiome | 557 | |
| chrX:53,088,446–53,088,904 | 93.3 kb | Distal (>10kb) Multiome | 204 | |
| chrX:53,093,602–53,094,629 | 98.6 kb | Distal (>10kb) Multiome | 585 | |
| chrX:53,224,805–53,225,756 | 229.9 kb | Distal (>10kb) Multiome | 825 |
Genomic view of the FAM156A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.