Enables oxaloacetate tautomerase activity. Involved in oxaloacetate metabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FAHD2A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FAHD2A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FAHD2A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr2:95,121,334–95,122,514 | 280.8 kb | Distal (>10kb) Multiome | 934 | |
| chr2:95,158,615–95,160,452 | 243.0 kb | Distal (>10kb) Multiome | 539 | |
| chr2:95,165,117–95,166,301 | 237.0 kb | Distal (>10kb) Multiome | 931 | |
| chr2:95,206,705–95,208,058 | 195.3 kb | Distal (>10kb) Multiome | 713 | |
| chr2:95,345,216–95,347,558 | 57.0 kb | Distal (>10kb) Multiome | 572 | |
| chr2:95,388,847–95,389,649 | 13.4 kb | Distal (>10kb) Multiome | 269 | |
| chr2:95,392,830–95,392,999 | 9.7 kb | Proximal (<10kb) | 24 | |
| chr2:95,401,933–95,403,542 | 89 bp | At TSS Multiome | 885 | |
| chr2:95,682,442–95,683,289 | 280.0 kb | Distal (>10kb) Multiome | 126 | |
| chr2:95,713,301–95,714,629 | 311.2 kb | Distal (>10kb) Multiome HiCAR | 154 |
Genomic view of the FAHD2A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.