Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for DDX52. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = DDX52 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of DDX52, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr17:37,358,363–37,360,066 | 284.1 kb | Distal (>10kb) Multiome | 859 | |
| chr17:37,406,418–37,407,500 | 236.4 kb | Distal (>10kb) Multiome | 822 | |
| chr17:37,488,914–37,490,446 | 153.6 kb | Distal (>10kb) Multiome | 759 | |
| chr17:37,608,867–37,609,901 | 34.0 kb | Distal (>10kb) Multiome | 930 | |
| chr17:37,643,162–37,643,681 | 39 bp | At TSS Multiome | 540 | |
| chr17:37,709,949–37,710,763 | 67.1 kb | Distal (>10kb) Multiome | 375 | |
| chr17:37,725,144–37,726,036 | 82.0 kb | Distal (>10kb) Multiome | 148 | |
| chr17:37,743,503–37,745,720 | 101.8 kb | Distal (>10kb) Multiome | 528 |
Genomic view of the DDX52 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.