Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for DDX51. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = DDX51 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of DDX51, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr12:131,894,077–131,895,155 | 249.8 kb | Distal (>10kb) Multiome | 460 | |
| chr12:131,895,483–131,896,833 | 248.1 kb | Distal (>10kb) Multiome | 784 | |
| chr12:131,928,499–131,930,478 | 215.2 kb | Distal (>10kb) Multiome | 908 | |
| chr12:131,949,435–131,950,660 | 194.5 kb | Distal (>10kb) Multiome | 770 | |
| chr12:132,083,735–132,085,216 | 60.2 kb | Distal (>10kb) Multiome | 882 | |
| chr12:132,143,424–132,145,177 | 63 bp | At TSS Multiome | 886 | |
| chr12:132,153,764–132,154,281 | 9.8 kb | Proximal (<10kb) Multiome | 467 | |
| chr12:132,189,320–132,190,290 | 45.5 kb | Distal (>10kb) Multiome | 452 | |
| chr12:132,437,261–132,437,736 | 293.2 kb | Distal (>10kb) Multiome | 153 | |
| chr12:132,559,692–132,561,628 | 415.7 kb | Distal (>10kb) Multiome HiCAR | 607 |
Genomic view of the DDX51 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.