Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translation. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CFAP418-AS1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CFAP418-AS1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CFAP418-AS1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr8:95,024,342–95,025,424 | 243.9 kb | Distal (>10kb) Multiome | 980 | |
| chr8:95,132,764–95,134,804 | 135.1 kb | Distal (>10kb) Multiome | 917 | |
| chr8:95,268,225–95,270,513 | 959 bp | At TSS Multiome | 1069 | |
| chr8:95,430,278–95,431,301 | 162.0 kb | Distal (>10kb) Multiome | 144 | |
| chr8:95,530,764–95,531,454 | 262.3 kb | Distal (>10kb) Multiome | 92 | |
| chr8:96,144,359–96,146,213 | 876.2 kb | Distal (>10kb) Multiome HiCAR | 434 |
Genomic view of the CFAP418-AS1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.