Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CCDC82. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CCDC82 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CCDC82, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:95,788,868–95,791,310 | 600.1 kb | Distal (>10kb) Multiome HiCAR | 1058 | |
| chr11:95,923,511–95,924,679 | 465.8 kb | Distal (>10kb) Multiome HiCAR | 950 | |
| chr11:96,167,040–96,167,627 | 222.5 kb | Distal (>10kb) Multiome | 97 | |
| chr11:96,180,222–96,181,389 | 208.9 kb | Distal (>10kb) Multiome | 133 | |
| chr11:96,211,587–96,212,750 | 177.5 kb | Distal (>10kb) Multiome | 391 | |
| chr11:96,243,217–96,244,039 | 146.5 kb | Distal (>10kb) Multiome | 569 | |
| chr11:96,342,718–96,343,737 | 46.6 kb | Distal (>10kb) Multiome | 568 | |
| chr11:96,389,261–96,390,676 | 12 bp | At TSS Multiome | 898 | |
| chr11:96,586,158–96,587,250 | 196.7 kb | Distal (>10kb) Multiome | 210 |
Genomic view of the CCDC82 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.