Predicted to enable calcium oxalate binding activity. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CCDC144A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CCDC144A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CCDC144A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr17:16,406,971–16,407,704 | 282.8 kb | Distal (>10kb) Multiome | 340 | |
| chr17:16,438,359–16,439,725 | 251.4 kb | Distal (>10kb) Multiome | 1006 | |
| chr17:16,442,894–16,444,373 | 246.4 kb | Distal (>10kb) Multiome | 388 | |
| chr17:16,491,363–16,492,722 | 198.0 kb | Distal (>10kb) Multiome | 312 | |
| chr17:16,535,515–16,536,276 | 154.5 kb | Distal (>10kb) Multiome HiCAR | 814 | |
| chr17:16,536,612–16,537,145 | 153.2 kb | Distal (>10kb) Multiome HiCAR | 360 | |
| chr17:16,568,720–16,569,381 | 121.1 kb | Distal (>10kb) Multiome | 379 | |
| chr17:16,588,994–16,589,833 | 100.8 kb | Distal (>10kb) Multiome | 573 | |
| chr17:16,653,205–16,654,064 | 36.5 kb | Distal (>10kb) Multiome | 830 |
Genomic view of the CCDC144A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.