Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in sperm principal piece. Predicted to be part of CatSper complex. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CATSPERB. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CATSPERB upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CATSPERB, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr14:91,413,560–91,414,125 | 256.2 kb | Distal (>10kb) Multiome | 171 | |
| chr14:91,417,256–91,419,093 | 250.9 kb | Distal (>10kb) Multiome | 961 | |
| chr14:91,509,196–91,511,114 | 159.4 kb | Distal (>10kb) Multiome | 1071 | |
| chr14:91,835,675–91,837,066 | 166.6 kb | Distal (>10kb) Multiome | 412 | |
| chr14:91,947,236–91,948,135 | 277.8 kb | Distal (>10kb) Multiome | 316 |
Genomic view of the CATSPERB locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.