CARD16

caspase recruitment domain family member 16 | COP, COP1, LLID-114769, PSEUDO-ICE

Enables several functions, including CARD domain binding activity; cysteine-type endopeptidase inhibitor activity; and enzyme binding activity. Involved in cellular response to lipopolysaccharide; regulation of gene expression; and regulation of signal transduction. Part of protease inhibitor complex. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 19 terms

CARD domain binding (GO:0050700)caspase binding (GO:0089720)cellular response to lipopolysaccharide (GO:0071222)cysteine-type endopeptidase activity (GO:0004197)cysteine-type endopeptidase inhibitor activity (GO:0004869)enzyme binding (GO:0019899)identical protein binding (GO:0042802)kinase binding (GO:0019900)negative regulation of interleukin-1 beta production (GO:0032691)negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)positive regulation of canonical NF-kappaB signal transduction (GO:0043123)protease inhibitor complex (GO:0097179)protein binding (GO:0005515)protein-containing complex (GO:0032991)protein-containing complex (GO:0032991)proteolysis (GO:0006508)regulation of apoptotic process (GO:0042981)regulation of interleukin-1 beta production (GO:0032651)

Expression (TPM)