Enables chromatin binding activity. Involved in heterochromatin formation and negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of chromatin silencing complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for BAHD1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = BAHD1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of BAHD1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr15:40,160,791–40,161,326 | 279.9 kb | Distal (>10kb) Multiome | 762 | |
| chr15:40,323,099–40,324,127 | 117.5 kb | Distal (>10kb) Multiome | 737 | |
| chr15:40,357,707–40,358,772 | 82.7 kb | Distal (>10kb) Multiome | 515 | |
| chr15:40,367,875–40,368,398 | 72.8 kb | Distal (>10kb) Multiome | 846 | |
| chr15:40,405,523–40,406,103 | 35.2 kb | Distal (>10kb) Multiome | 672 | |
| chr15:40,440,664–40,441,222 | 38 bp | At TSS Multiome | 440 | |
| chr15:40,470,654–40,471,315 | 30.0 kb | Distal (>10kb) Multiome | 463 | |
| chr15:40,511,458–40,512,083 | 70.8 kb | Distal (>10kb) Multiome | 646 | |
| chr15:40,593,777–40,594,776 | 153.2 kb | Distal (>10kb) Multiome | 899 | |
| chr15:40,694,639–40,695,262 | 254.1 kb | Distal (>10kb) Multiome | 831 |
Genomic view of the BAHD1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.