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ASCL4 Overview
ASCL4
achaete-scute family bHLH transcription factor 4 | HASH4, bHLHa44

Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]

Biological processes 17 terms
DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)DNA-binding transcription repressor activity, RNA polymerase II-specific (GO:0001227)RNA polymerase II transcription regulator complex (GO:0090575)RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)animal organ development (GO:0048513)chromatin (GO:0000785)epithelium development (GO:0060429)negative regulation of transcription by RNA polymerase II (GO:0000122)nucleus (GO:0005634)protein binding (GO:0005515)protein dimerization activity (GO:0046983)regulation of transcription by RNA polymerase II (GO:0006357)regulation of transcription by RNA polymerase II (GO:0006357)skin development (GO:0043588)transcription regulator complex (GO:0005667)
Expression (TPM)
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