ASCL3

achaete-scute family bHLH transcription factor 3 | HASH3, Sgn1, bHLHa42

Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]

Biological processes 21 terms

DNA binding (GO:0003677)DNA binding (GO:0003677)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)DNA-binding transcription repressor activity, RNA polymerase II-specific (GO:0001227)RNA polymerase II transcription regulator complex (GO:0090575)RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)animal organ development (GO:0048513)chromatin (GO:0000785)epithelium development (GO:0060429)negative regulation of transcription by RNA polymerase II (GO:0000122)nucleus (GO:0005634)positive regulation of transcription by RNA polymerase II (GO:0045944)protein binding (GO:0005515)protein dimerization activity (GO:0046983)regulation of transcription by RNA polymerase II (GO:0006357)salivary gland development (GO:0007431)sensory epithelium regeneration (GO:0070654)tissue homeostasis (GO:0001894)transcription regulator complex (GO:0005667)

Expression (TPM)