ADGRG1
adhesion G protein-coupled receptor G1 | TM7LN4, TM7XN1, GPR56

This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Biological processes 67 terms
G protein-coupled receptor activity (GO:0004930)G protein-coupled receptor activity (GO:0004930)G protein-coupled receptor activity (GO:0004930)G protein-coupled receptor activity (GO:0004930)G protein-coupled receptor activity (GO:0004930)G protein-coupled receptor activity (GO:0004930)G protein-coupled receptor signaling pathway (GO:0007186)G protein-coupled receptor signaling pathway (GO:0007186)G protein-coupled receptor signaling pathway (GO:0007186)Rho protein signal transduction (GO:0007266)Rho-activating G protein-coupled receptor signaling pathway (GO:0160221)Rho-activating G protein-coupled receptor signaling pathway (GO:0160221)Rho-activating G protein-coupled receptor signaling pathway (GO:0160221)anatomical structure formation involved in morphogenesis (GO:0048646)angiogenesis (GO:0001525)brain development (GO:0007420)brain development (GO:0007420)cell adhesion (GO:0007155)cell adhesion (GO:0007155)cell migration (GO:0016477)cell migration (GO:0016477)cell surface receptor signaling pathway (GO:0007166)cell-cell signaling (GO:0007267)cerebral cortex radial glia-guided migration (GO:0021801)cerebral cortex radial glia-guided migration (GO:0021801)collagen binding (GO:0005518)collagen binding (GO:0005518)extracellular exosome (GO:0070062)extracellular matrix binding (GO:0050840)extracellular matrix binding (GO:0050840)extracellular region (GO:0005576)glial limiting end-foot (GO:0097451)glial limiting end-foot (GO:0097451)heparin binding (GO:0008201)heparin binding (GO:0008201)heparin binding (GO:0008201)layer formation in cerebral cortex (GO:0021819)layer formation in cerebral cortex (GO:0021819)membrane (GO:0016020)membrane (GO:0016020)membrane raft (GO:0045121)negative regulation of cell population proliferation (GO:0008285)negative regulation of ferroptosis (GO:0110076)negative regulation of ferroptosis (GO:0110076)negative regulation of neuron migration (GO:2001223)negative regulation of neuron migration (GO:2001223)phosphatidylserine binding (GO:0001786)phospholipase C-activating G protein-coupled receptor signaling pathway (GO:0007200)plasma membrane (GO:0005886)plasma membrane (GO:0005886)plasma membrane (GO:0005886)plasma membrane (GO:0005886)plasma membrane (GO:0005886)plasma membrane (GO:0005886)positive regulation of Rho protein signal transduction (GO:0035025)positive regulation of Rho protein signal transduction (GO:0035025)positive regulation of cell adhesion (GO:0045785)positive regulation of signal transduction (GO:0009967)positive regulation of vascular endothelial growth factor signaling pathway (GO:1900748)protein binding (GO:0005515)regulation of cell population proliferation (GO:0042127)regulation of platelet aggregation (GO:0090330)regulation of platelet aggregation (GO:0090330)seminiferous tubule development (GO:0072520)synapse pruning (GO:0098883)transmembrane signaling receptor activity (GO:0004888)tube development (GO:0035295)
Expression (TPM)
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