The protein encoded by this gene is a mitochondrial acyl-CoA thioesterase of unknown function. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Transcription factors with Perturb-seq knockdown data for ACOT9. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ACOT9 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ACOT9, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chrX:23,667,233–23,667,983 | 75.8 kb | Distal (>10kb) Multiome | 695 | |
| chrX:23,742,772–23,743,685 | 27 bp | At TSS Multiome | 635 | |
| chrX:23,782,718–23,783,632 | 39.8 kb | Distal (>10kb) Multiome | 741 | |
| chrX:23,907,232–23,908,257 | 164.6 kb | Distal (>10kb) Multiome HiCAR | 770 | |
| chrX:24,024,718–24,026,097 | 282.2 kb | Distal (>10kb) Multiome | 765 |
Genomic view of the ACOT9 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.